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Dimitrios Tsikas Selected Research

Lysine (L-Lysine)

4/2022Pilot Study on Acute Effects of Pharmacological Intraperitoneal L-Homoarginine on Homeostasis of Lysine and Other Amino Acids in a Rat Model of Isoprenaline-Induced Takotsubo Cardiomyopathy.
4/2022Profile of urinary amino acids and their post-translational modifications (PTM) including advanced glycation end-products (AGEs) of lysine, arginine and cysteine in lean and obese ZSF1 rats.
1/2022Advanced Glycation End-Products (AGEs) of Lysine and Effects of Anti-TCR/Anti-TNF-α Antibody-Based Therapy in the LEW.1AR1-iddm Rat, an Animal Model of Human Type 1 Diabetes.
6/2019Asymmetric dimethylation and citrullination of proteinic arginine and homoarginine synthesis in human Helicobacter pylori infection.

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Dimitrios Tsikas Research Topics

Disease

10Coronary Artery Disease (Coronary Atherosclerosis)
11/2023 - 11/2005
8Hypertension (High Blood Pressure)
11/2021 - 04/2002
7Body Weight (Weight, Body)
09/2022 - 08/2004
7Atherosclerosis
07/2018 - 08/2004
6Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
03/2024 - 09/2015
6Cardiovascular Diseases (Cardiovascular Disease)
04/2020 - 12/2003
5Inflammation (Inflammations)
04/2024 - 09/2005
5Type 2 Diabetes Mellitus (MODY)
03/2024 - 04/2005
5Rheumatoid Arthritis
09/2022 - 11/2011
4Peripheral Arterial Occlusive Disease 1
11/2023 - 01/2003
4Heart Failure
10/2021 - 08/2008
4MELAS Syndrome (Syndrome, MELAS)
01/2018 - 11/2016
4Myocardial Infarction
05/2009 - 04/2006
3Erectile Dysfunction
10/2023 - 11/2002
3Kidney Diseases (Kidney Disease)
10/2023 - 02/2009
3Hyperlipidemias (Hyperlipidemia)
01/2023 - 12/2015
3Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2023 - 01/2020
3Takotsubo Cardiomyopathy
04/2022 - 12/2013
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2022 - 09/2015
3Overweight
06/2019 - 09/2015
3Chronic Renal Insufficiency
06/2019 - 10/2016
3Pre-Eclampsia (Preeclampsia)
01/2018 - 05/2003
3Obesity
09/2015 - 05/2014
3Hemolysis
11/2012 - 04/2009
3Hypercholesterolemia
08/2012 - 02/2004
3Neoplasms (Cancer)
04/2011 - 04/2009
2Fibrosis (Cirrhosis)
07/2023 - 08/2008
2Hyperglycemia
01/2023 - 04/2022
2Cystic Fibrosis (Mucoviscidosis)
11/2020 - 06/2020
2Lung Diseases (Lung Disease)
06/2020 - 01/2012
2Infections
06/2019 - 06/2009
2Dyslipidemias (Dyslipidemia)
07/2018 - 05/2016
2Dehydration (Water Stress)
01/2018 - 01/2016
2Ischemia
01/2017 - 09/2015
2Hypercapnia
01/2016 - 05/2013
2Pulmonary Edema
01/2016 - 08/2008
2Albuminuria
09/2015 - 08/2011
2Weight Loss (Weight Reduction)
09/2015 - 01/2014
2Hyperoxia
01/2015 - 09/2012
2Pulmonary Hypertension
12/2012 - 04/2009
2Rheumatic Diseases (Rheumatism)
05/2011 - 11/2009
2End Stage Liver Disease
02/2009 - 05/2007
2Infarction (Infarctions)
08/2008 - 04/2006

Drug/Important Bio-Agent (IBA)

30Arginine (L-Arginine)FDA Link
11/2023 - 01/2003
29Nitric Oxide (Nitrogen Monoxide)FDA Link
09/2023 - 08/2003
22NitritesIBA
01/2023 - 09/2005
21N,N-dimethylarginine (asymmetric dimethylarginine)IBA
01/2023 - 05/2003
18NitratesIBA
01/2023 - 08/2004
13HomoarginineIBA
04/2022 - 05/2014
11Nitric Oxide Synthase (NO Synthase)IBA
09/2023 - 12/2003
8Biomarkers (Surrogate Marker)IBA
10/2023 - 04/2009
8CreatinineIBA
09/2023 - 05/2007
6Proteins (Proteins, Gene)FDA Link
06/2019 - 08/2008
5Amino AcidsFDA Link
09/2023 - 12/2015
5Malondialdehyde (Propanedial)IBA
09/2023 - 01/2010
5CitrullineIBA
02/2023 - 12/2006
4Metformin (Glucophage)FDA LinkGeneric
03/2024 - 10/2018
4Lysine (L-Lysine)FDA Link
04/2022 - 06/2019
4S-NitrosothiolsIBA
07/2018 - 11/2002
4Carbonic Anhydrases (Carbonic Anhydrase)IBA
01/2018 - 04/2015
4Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
10/2013 - 05/2003
4erucylphosphocholineIBA
11/2007 - 11/2005
3AcidsIBA
08/2022 - 11/2009
3symmetric dimethylarginineIBA
01/2018 - 09/2015
3Glucose (Dextrose)FDA LinkGeneric
12/2015 - 01/2014
3EnzymesIBA
09/2015 - 09/2010
3N(G),N(G')-dimethylarginineIBA
09/2015 - 12/2003
33-nitrotyrosineIBA
05/2014 - 11/2005
2Fatty Acids (Saturated Fatty Acids)IBA
04/2024 - 01/2023
2CollagenIBA
07/2023 - 02/2019
2dimethylamine (dimethylamine nitrate)IBA
01/2023 - 05/2012
2LipidsIBA
01/2023 - 12/2015
2Methylphenidate (Ritalin)FDA LinkGeneric
01/2023 - 01/2020
2Acetaminophen (Paracetamol)FDA LinkGeneric
09/2022 - 09/2014
2IsotopesIBA
06/2022 - 06/2019
2Anti-Bacterial Agents (Antibiotics)IBA
11/2020 - 08/2007
23,4-dihydroxyphenylglycolIBA
06/2020 - 05/2011
2CreatineIBA
06/2020 - 05/2019
2CatecholaminesIBA
06/2020 - 12/2013
2PotassiumIBA
05/2019 - 09/2014
2Apolipoproteins E (ApoE)IBA
07/2018 - 08/2013
2Indicators and Reagents (Reagents)IBA
01/2018 - 01/2012
2Protons (Proton)IBA
01/2018 - 01/2017
2Surface-Active Agents (Surfactants)IBA
01/2016 - 09/2005
2Dietary Fats (Dietary Fat)IBA
12/2015 - 05/2014
2Urea (Carbamide)FDA LinkGeneric
09/2015 - 12/2006
2Human Serum AlbuminFDA LinkGeneric
09/2015 - 04/2011
2Atorvastatin (Lipitor)FDA Link
04/2015 - 08/2013
2IonsIBA
09/2014 - 06/2009
2Oleic Acid (Oleate)IBA
06/2014 - 09/2010
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
08/2013 - 04/2006
2dimethylargininaseIBA
05/2012 - 11/2011
2Peroxidase (Myeloperoxidase)IBA
12/2011 - 11/2009
2dimethylarginineIBA
12/2011 - 11/2011
2Angiotensin IIIBA
04/2005 - 04/2002

Therapy/Procedure

8Therapeutics
04/2024 - 04/2009
5Oral Administration
11/2023 - 04/2009
3Transplantation
03/2019 - 09/2015
3Kidney Transplantation
03/2019 - 02/2009
2Protein-Restricted Diet (Diet, Protein Restricted)
05/2019 - 05/2012